BDBM285505 4-{4-Cyano-2-[({(2′R,4S)-7-[(2-methoxyethyl)carbamoyl]-2,3-dihydrospiro[chromene-4,1′-cyclopropan]-2′-yl}carbonyl)amino]phenyl}butanoic acid::US10077247, Example 28-2

SMILES COCCNC(=O)c1ccc2c(OCC[C@]22C[C@H]2C(=O)Nc2cc(ccc2CCCC(O)=O)C#N)c1

InChI Key InChIKey=LFBIGDHEMXWJMI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 285505   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM285505(US10077247, Example 28-2 | 4-{4-Cyano-2-[({(2̸...)
Affinity DataIC50: 6.90nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent