BDBM285512 4-[4-Cyano-2-({[(1S,2R)-3′,3′-dimethyl-6′-(methylcarbamoyl)-2′,3′-dihydrospiro[cyclopropane-1, 1′-inden]-2-yl]carbonyl}amino)phenyl]butanoic acid::US10077247, Example 38-2

SMILES CNC(=O)c1ccc2c(c1)[C@@]1(C[C@H]1C(=O)Nc1cc(ccc1CCCC(O)=O)C#N)CC2(C)C

InChI Key InChIKey=ILHOIEZMIAPIJM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 285512   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM285512(US10077247, Example 38-2 | 4-[4-Cyano-2-({[(1S,2R)...)
Affinity DataIC50: 4.30nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent