BDBM285535 Azetidin-1-yl[3-(pyrazolo[1,5-a]pyridin-6-yl)imidazo[1,2-b]pyridazin-2-yl]methanone (8)::US10077269, Example 8::US10669279, Example 8

SMILES O=C(N1CCC1)c1nc2cccnn2c1-c1ccc2ccnn2c1

InChI Key InChIKey=AAWHVDHSXWEWJR-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 285535   

LigandPNGBDBM285535(US10077269, Example 8 | Azetidin-1-yl[3-(pyrazolo[...)
Affinity DataIC50: 20nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285535(US10077269, Example 8 | Azetidin-1-yl[3-(pyrazolo[...)
Affinity DataIC50: 20nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285535(US10077269, Example 8 | Azetidin-1-yl[3-(pyrazolo[...)
Affinity DataIC50: 41.3nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285535(US10077269, Example 8 | Azetidin-1-yl[3-(pyrazolo[...)
Affinity DataIC50: 41.3nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285535(US10077269, Example 8 | Azetidin-1-yl[3-(pyrazolo[...)
Affinity DataIC50: 64.9nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285535(US10077269, Example 8 | Azetidin-1-yl[3-(pyrazolo[...)
Affinity DataIC50: 64.9nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandPNGBDBM285535(US10077269, Example 8 | Azetidin-1-yl[3-(pyrazolo[...)
Affinity DataIC50: 5.44E+3nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandPNGBDBM285535(US10077269, Example 8 | Azetidin-1-yl[3-(pyrazolo[...)
Affinity DataIC50: 5.44E+3nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent