BDBM285538 N-cyclopropyl-3-(3,4-di-chlorophenyl)imidazo[1,2-b]pyridazine-2-carboxamide::US10077269, Example 11::US10669279, Example 11::US9598421, Example 11

SMILES Clc1ccc(cc1Cl)-c1c(nc2cccnn12)C(=O)NC1CC1

InChI Key InChIKey=HJVCDCPLKNQXFO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 285538   

LigandPNGBDBM285538(US10077269, Example 11 | N-cyclopropyl-3-(3,4-di-c...)
Affinity DataIC50: 1.60nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
Go to US Patent

LigandPNGBDBM285538(US10077269, Example 11 | N-cyclopropyl-3-(3,4-di-c...)
Affinity DataIC50: 334nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
Go to US Patent

LigandPNGBDBM285538(US10077269, Example 11 | N-cyclopropyl-3-(3,4-di-c...)
Affinity DataIC50: 1.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent

LigandPNGBDBM285538(US10077269, Example 11 | N-cyclopropyl-3-(3,4-di-c...)
Affinity DataIC50: 334nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent

LigandPNGBDBM285538(US10077269, Example 11 | N-cyclopropyl-3-(3,4-di-c...)
Affinity DataIC50: 1.60nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
Go to US Patent

LigandPNGBDBM285538(US10077269, Example 11 | N-cyclopropyl-3-(3,4-di-c...)
Affinity DataIC50: 334nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
Go to US Patent