BDBM285612 3-(4-chloro-3-fluorophenyl)-N-(1H-pyrazol-4-yl)imidazo[1,2-b]pyridazine-2-carboxamide::US10077269, Example 82::US10669279, Example 82::US9598421, Example 82

SMILES Fc1cc(ccc1Cl)-c1c(nc2cccnn12)C(=O)Nc1cn[nH]c1

InChI Key InChIKey=YEUSBANVZAFKBV-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 285612   

LigandPNGBDBM285612(US10077269, Example 82 | 3-(4-chloro-3-fluoropheny...)
Affinity DataIC50: 12nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
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LigandPNGBDBM285612(US10077269, Example 82 | 3-(4-chloro-3-fluoropheny...)
Affinity DataIC50: 5.14nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
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LigandPNGBDBM285612(US10077269, Example 82 | 3-(4-chloro-3-fluoropheny...)
Affinity DataIC50: 43.4nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
Go to US Patent

LigandPNGBDBM285612(US10077269, Example 82 | 3-(4-chloro-3-fluoropheny...)
Affinity DataIC50: 56.5nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
Go to US Patent

LigandPNGBDBM285612(US10077269, Example 82 | 3-(4-chloro-3-fluoropheny...)
Affinity DataIC50: 12nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent

LigandPNGBDBM285612(US10077269, Example 82 | 3-(4-chloro-3-fluoropheny...)
Affinity DataIC50: 5.14nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent

LigandPNGBDBM285612(US10077269, Example 82 | 3-(4-chloro-3-fluoropheny...)
Affinity DataIC50: 43.4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
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LigandPNGBDBM285612(US10077269, Example 82 | 3-(4-chloro-3-fluoropheny...)
Affinity DataIC50: 56.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent

LigandPNGBDBM285612(US10077269, Example 82 | 3-(4-chloro-3-fluoropheny...)
Affinity DataIC50: 12nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
Go to US Patent

LigandPNGBDBM285612(US10077269, Example 82 | 3-(4-chloro-3-fluoropheny...)
Affinity DataIC50: 5.14nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
Go to US Patent

LigandPNGBDBM285612(US10077269, Example 82 | 3-(4-chloro-3-fluoropheny...)
Affinity DataIC50: 43.4nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
Go to US Patent

LigandPNGBDBM285612(US10077269, Example 82 | 3-(4-chloro-3-fluoropheny...)
Affinity DataIC50: 56.5nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
Go to US Patent