BDBM285613 US10077269, Example 83::US10669279, Example 83::US9598421, Example 83::azetidin-1-yl[3-(3,4-dichloro-phenyl)imidazo[1,2-b]pyridazin-2-yl]methanone

SMILES Clc1ccc(cc1Cl)-c1c(nc2cccnn12)C(=O)N1CCC1

InChI Key InChIKey=VGRIHMHLBGLHHB-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 285613   

LigandPNGBDBM285613(US10077269, Example 83 | azetidin-1-yl[3-(3,4-dich...)
Affinity DataIC50: 6.21nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
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LigandPNGBDBM285613(US10077269, Example 83 | azetidin-1-yl[3-(3,4-dich...)
Affinity DataIC50: 5.39nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
Go to US Patent

LigandPNGBDBM285613(US10077269, Example 83 | azetidin-1-yl[3-(3,4-dich...)
Affinity DataIC50: 40nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
Go to US Patent

LigandPNGBDBM285613(US10077269, Example 83 | azetidin-1-yl[3-(3,4-dich...)
Affinity DataIC50: 495nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
Go to US Patent

LigandPNGBDBM285613(US10077269, Example 83 | azetidin-1-yl[3-(3,4-dich...)
Affinity DataIC50: 6.21nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent

LigandPNGBDBM285613(US10077269, Example 83 | azetidin-1-yl[3-(3,4-dich...)
Affinity DataIC50: 5.39nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent

LigandPNGBDBM285613(US10077269, Example 83 | azetidin-1-yl[3-(3,4-dich...)
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent

LigandPNGBDBM285613(US10077269, Example 83 | azetidin-1-yl[3-(3,4-dich...)
Affinity DataIC50: 495nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent

LigandPNGBDBM285613(US10077269, Example 83 | azetidin-1-yl[3-(3,4-dich...)
Affinity DataIC50: 6.21nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
Go to US Patent

LigandPNGBDBM285613(US10077269, Example 83 | azetidin-1-yl[3-(3,4-dich...)
Affinity DataIC50: 5.39nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
Go to US Patent

LigandPNGBDBM285613(US10077269, Example 83 | azetidin-1-yl[3-(3,4-dich...)
Affinity DataIC50: 40nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
Go to US Patent

LigandPNGBDBM285613(US10077269, Example 83 | azetidin-1-yl[3-(3,4-dich...)
Affinity DataIC50: 495nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
Go to US Patent