BDBM286082 1-benzyl-N-(3-(piperazin-1-ylmethyl)benzofuran-5-yl)-1H-pyrazole-4-carboxamide::BDBM342160::US10081632, Compound 9::US10758530, Compound 9

SMILES O=C(Nc1ccc2occ(CN3CCNCC3)c2c1)c1cnn(Cc2ccccc2)c1

InChI Key InChIKey=FKDVCNBKHGGOCX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 286082   

TargetRibosomal protein S6 kinase alpha-3(Human)
Phoenix Molecular Designs

US Patent
LigandPNGBDBM286082(US10758530, Compound 9 | US10081632, Compound 9 | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:The assay was initiated by the addition of 33P-ATP and the reaction mixture incubated at 30° C. for 15 minutes. After the incubation period, the assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2019
Entry Details
Go to US Patent

TargetRibosomal protein S6 kinase alpha-2(Human)
Phoenix Molecular Design

US Patent
LigandPNGBDBM286082(US10758530, Compound 9 | US10081632, Compound 9 | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
Go to US Patent

TargetRibosomal protein S6 kinase alpha-2(Human)
Phoenix Molecular Design

US Patent
LigandPNGBDBM286082(US10758530, Compound 9 | US10081632, Compound 9 | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Radioisotope assays were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radioactive workin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
Go to US Patent