BDBM286093 (R)-9-methyl-N-(1-((1-methylpiperidin-4-yl)methyl)-1H-pyrazol-4-yl)-6-oxo-6,7,8,9-tetrahydropyrido[3′,2′:4,5]pyrrolo[1,2-a]pyrazine-2-carboxamide::US10081632, Compound 20::US10758530, Compound 20::US9771366, Compound 20

SMILES C[C@@H]1CNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnn(CC2CCN(C)CC2)c1

InChI Key InChIKey=LLJNOVYIPCASQO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 286093   

TargetRibosomal protein S6 kinase alpha-3(Human)
Phoenix Molecular Designs

US Patent
LigandPNGBDBM286093(US10081632, Compound 20 | (R)-9-methyl-N-(1-((1-me...)
Affinity DataIC50: 1.24E+5nMAssay Description:The assay was initiated by the addition of 33P-ATP and the reaction mixture incubated at 30° C. for 15 minutes. After the incubation period, the assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2019
Entry Details
Go to US Patent

TargetRibosomal protein S6 kinase alpha-2(Human)
Phoenix Molecular Design

US Patent
LigandPNGBDBM286093(US10081632, Compound 20 | (R)-9-methyl-N-(1-((1-me...)
Affinity DataIC50: 1.24E+5nMAssay Description:Radioisotope assays (SignalChem) were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2019
Entry Details
Go to US Patent

TargetRibosomal protein S6 kinase alpha-2(Human)
Phoenix Molecular Design

US Patent
LigandPNGBDBM286093(US10081632, Compound 20 | (R)-9-methyl-N-(1-((1-me...)
Affinity DataIC50: 124nMAssay Description:Radioisotope assays were performed for the evaluation of the kinase target profiling and all assays were performed in a designated radioactive workin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
Go to US Patent