BDBM286224 4-(6-fluoro-3-ethylimidazo[1,2- a]pyridin-2-yl)isoquinoline::US9518055, Example 25

SMILES Cc1c(nc2ccc(F)cn12)-c1cncc2ccccc12

InChI Key InChIKey=RYLIJQNPHJXVOG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 286224   

TargetCytochrome P450 11B2, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM286224(US9518055, Example 25 | 4-(6-fluoro-3-ethylimidazo...)
Affinity DataIC50: 0.100nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM286224(US9518055, Example 25 | 4-(6-fluoro-3-ethylimidazo...)
Affinity DataIC50: 14.8nMAssay Description:V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
US Patent