BDBM28753 2-[4-({[3-(4-tert-butylphenyl)-1,2,4-thiadiazol-5-yl]methyl}sulfanyl)-2-methylphenoxy]-2-methylpropanoic acid::[1,2,4]thiadiazole derivative, 36

SMILES Cc1cc(SCc2nc(ns2)-c2ccc(cc2)C(C)(C)C)ccc1OC(C)(C)C(O)=O

InChI Key InChIKey=RZGXJNCOBNXAPV-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 28753   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM28753(2-[4-({[3-(4-tert-butylphenyl)-1,2,4-thiadiazol-5-...)
Affinity DataEC50:  64nMAssay Description:The HEK293 cells were co-transfected with DNA constructs containing the ligand-binding domain of PPAR and Gal4-luciferase reporter. The luciferase ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM28753(2-[4-({[3-(4-tert-butylphenyl)-1,2,4-thiadiazol-5-...)
Affinity DataEC50: >3.00E+3nMAssay Description:The HEK293 cells were co-transfected with DNA constructs containing the ligand-binding domain of PPAR and Gal4-luciferase reporter. The luciferase ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM28753(2-[4-({[3-(4-tert-butylphenyl)-1,2,4-thiadiazol-5-...)
Affinity DataEC50:  93nMAssay Description:The HEK293 cells were co-transfected with DNA constructs containing the ligand-binding domain of PPAR and Gal4-luciferase reporter. The luciferase ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed