BDBM28758 1-{2-methyl-4-[({3-[4-(trifluoromethoxy)phenyl]-1,2,4-thiadiazol-5-yl}methyl)sulfanyl]phenoxy}cyclopentane-1-carboxylic acid::[1,2,4]thiadiazole derivative, 57

SMILES Cc1cc(SCc2nc(ns2)-c2ccc(OC(F)(F)F)cc2)ccc1OC1(CCCC1)C(O)=O

InChI Key InChIKey=VKQSDPFDBIOVSF-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 28758   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM28758(1-{2-methyl-4-[({3-[4-(trifluoromethoxy)phenyl]-1,...)
Affinity DataEC50:  736nMAssay Description:The HEK293 cells were co-transfected with DNA constructs containing the ligand-binding domain of PPAR and Gal4-luciferase reporter. The luciferase ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM28758(1-{2-methyl-4-[({3-[4-(trifluoromethoxy)phenyl]-1,...)
Affinity DataEC50: >3.00E+3nMAssay Description:The HEK293 cells were co-transfected with DNA constructs containing the ligand-binding domain of PPAR and Gal4-luciferase reporter. The luciferase ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM28758(1-{2-methyl-4-[({3-[4-(trifluoromethoxy)phenyl]-1,...)
Affinity DataEC50: >1.00E+3nMAssay Description:The HEK293 cells were co-transfected with DNA constructs containing the ligand-binding domain of PPAR and Gal4-luciferase reporter. The luciferase ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM28758(1-{2-methyl-4-[({3-[4-(trifluoromethoxy)phenyl]-1,...)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at human PPARgamma-Gal4 in HEK293 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM28758(1-{2-methyl-4-[({3-[4-(trifluoromethoxy)phenyl]-1,...)
Affinity DataEC50:  736nMAssay Description:Agonist activity at human PPARalpha-Gal4 in HEK293 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM28758(1-{2-methyl-4-[({3-[4-(trifluoromethoxy)phenyl]-1,...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human PPARdelta-Gal4 in HEK293 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed