BDBM28764 2-[3-chloro-4-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-5-phenyl-1,2-oxazol-3-yl)phenyl]acetic acid::CHEMBL211473::trisubstituted isoxazole, 1

SMILES OC(=O)Cc1ccc(-c2noc(c2C(=O)NCCOc2ccc(Cl)cc2Cl)-c2ccccc2)c(Cl)c1

InChI Key InChIKey=SUEZNXXKBMUSQM-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 28764   

LigandPNGBDBM28764(CHEMBL211473 | 2-[3-chloro-4-(4-{[2-(2,4-dichlorop...)
Affinity DataEC50:  80nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2009
Entry Details Article
PubMed
LigandPNGBDBM28764(CHEMBL211473 | 2-[3-chloro-4-(4-{[2-(2,4-dichlorop...)
Affinity DataEC50: >1.00E+4nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2009
Entry Details Article
PubMed
LigandPNGBDBM28764(CHEMBL211473 | 2-[3-chloro-4-(4-{[2-(2,4-dichlorop...)
Affinity DataEC50: >1.00E+4nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2009
Entry Details Article
PubMed
LigandPNGBDBM28764(CHEMBL211473 | 2-[3-chloro-4-(4-{[2-(2,4-dichlorop...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PPARgamma by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM28764(CHEMBL211473 | 2-[3-chloro-4-(4-{[2-(2,4-dichlorop...)
Affinity DataEC50:  80nMAssay Description:Agonist activity at PPARdelta by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM28764(CHEMBL211473 | 2-[3-chloro-4-(4-{[2-(2,4-dichlorop...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PPARalpha by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed