BDBM288193 2-(Difluoromethyl)-6-(trifluoromethyl)-5-(7-(trifluoromethyl)-1H-::US10087185, Example 11

SMILES FC(F)c1nc2ccc(c(-c3cc(c4[nH]ncc4c3)C(F)(F)F)n2n1)C(F)(F)F

InChI Key InChIKey=XULMXTJVIJVWCH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288193   

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM288193(US10087185, Example 11 | 2-(Difluoromethyl)-6-(tri...)
Affinity DataIC50: 0.158nMpH: 7.4Assay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
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Date in BDB:
1/17/2019
Entry Details
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