BDBM288600 (E)-3-(3,5-difluoro-4-((6S,8R/6R,8S)-7-(2-fluoro-2-methylpropyl)-8-methyl-2,3,6,7,8,9-hexahydro-[1,4]dioxino[2,3-g]isoquinolin-6-yl)phenyl)acrylic acid::US10087191, Example 2

SMILES COC(=O)\C=C\c1cc(F)c(C2N(CC(C)(C)F)C(C)Cc3cc4OCCOc4cc23)c(F)c1

InChI Key InChIKey=YYDJDTVNLJDVKY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288600   

TargetG-protein coupled estrogen receptor 1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM288600((E)-3-(3,5-difluoro-4-((6S,8R/6R,8S)-7-(2-fluoro-2...)
Affinity DataIC50: 3.20nMAssay Description:The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
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