BDBM28921 (2S,3S)-N-(4-bromophenyl)-1-hydroxy-3-methylpentane-2-sulfonamido::BMCL184232 Compound 2e::Begacestat analogue, 2
SMILES CC[C@H](C)[C@@H](CO)NS(=O)(=O)c1ccc(Br)cc1
InChI Key InChIKey=KRCRTCGHANKNGN-UHFFFAOYSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 28921
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit PEN-2/Nicastrin [34-709]/Presenilin-1(Human)
Wyeth Research
Wyeth Research
Affinity DataEC50: 2.21E+3nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit PEN-2/Nicastrin [34-709]/Presenilin-1(Human)
Wyeth Research
Wyeth Research
Affinity DataEC50: 2.21E+3nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
