BDBM289448 1-(4-(6-amino-5- (trifluoromethoxy)- pyridin-3-yl)-1-(3- morpholinobicyclo- [1.1.1]pentan-1-yl)-1H- imidazol-2-yl)cyclo- propane-1-carbonitrile::US10093664, Example 29

SMILES Nc1ncc(cc1OC(F)(F)F)-c1cn(c(n1)C1(CC1)C#N)C12CC(C1)(C2)N1CCOCC1

InChI Key InChIKey=ORFJPDZQANRKRH-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289448   

TargetMitogen-activated protein kinase kinase kinase 12(Human)
The University of Texas System

US Patent
LigandPNGBDBM289448(US10093664, Example 29 | 1-(4-(6-amino-5- (trifluo...)
Affinity DataKd:  20nMAssay Description:The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
US Patent