BDBM289869 N-((R)-1-{6-[5-(2H-Pyrazol-3-yl)- pyridin-2-yloxy]-naphthalen-2- ylmethyl}-pyrrolidin-3-yl)-acetamide::US9573957, Example 12

SMILES CC(=O)N[C@@H]1CCN(Cc2ccc3cc(Oc4ccc(cn4)-c4ccn[nH]4)ccc3c2)C1

InChI Key InChIKey=HFSOQQPSRWJILZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289869   

TargetLeukotriene A-4 hydrolase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289869(N-((R)-1-{6-[5-(2H-Pyrazol-3-yl)- pyridin-2-yloxy]...)
Affinity DataIC50: 0.340nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
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