BDBM289911 2,2-Dimethyl-3-oxo-3-(8-{6-[5-(2H- pyrazol-3-yl)-pyridin-2-yloxy]-quinolin- 2-ylmethyl}-3,8-diaza-bicyclo[3.2.1]oct- 3-yl)-propionitrile::US9573957, Example 51

SMILES CC(C)(C#N)C(=O)N1CC2CCC(C1)N2Cc1ccc2cc(Oc3ccc(cn3)-c3ccn[nH]3)ccc2n1

InChI Key InChIKey=HZOXZAPKRZLYRY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289911   

TargetLeukotriene A-4 hydrolase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289911(2,2-Dimethyl-3-oxo-3-(8-{6-[5-(2H- pyrazol-3-yl)-p...)
Affinity DataIC50: 0.730nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
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