BDBM289956 2-Methoxy-1-(4-{6-[4-(2H-pyrazol- 3-yl)-phenoxy]-imidazo[1,2-a]pyridin- 2-ylmethyl}-piperazin-1-yl)-ethanone::US9573957, Example 89

SMILES COCC(=O)N1CCN(Cc2cn3cc(Oc4ccc(cc4)-c4ccn[nH]4)ccc3n2)CC1

InChI Key InChIKey=BMBMEATZJUBCOF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289956   

TargetLeukotriene A-4 hydrolase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289956(2-Methoxy-1-(4-{6-[4-(2H-pyrazol- 3-yl)-phenoxy]-i...)
Affinity DataIC50: 0.660nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2019
Entry Details
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