BDBM29141 substituted chalcone, 5h

SMILES COc1ccc(cc1)C(=O)\C=C\c1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=TWYBNKWJRLRNCS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 29141   

TargetAmine oxidase [flavin-containing] B(Human)
Sapienza University of Rome

LigandPNGBDBM29141(substituted chalcone, 5h)
Affinity DataIC50: 450nMpH: 7.4 T: 2°CAssay Description:The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Sapienza University of Rome

LigandPNGBDBM29141(substituted chalcone, 5h)
Affinity DataAssay Description:The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Sapienza University of Rome

LigandPNGBDBM29141(substituted chalcone, 5h)
Affinity DataIC50: 4.47E+5nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed