BDBM29144 substituted chalcone, 5k

SMILES Oc1ccccc1C(=O)\C=C\c1ccc(Cl)cc1

InChI Key InChIKey=ZKBILMWSVPPRAT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 29144   

TargetAmine oxidase [flavin-containing] B(Human)
Sapienza University of Rome

LigandPNGBDBM29144(substituted chalcone, 5k)
Affinity DataIC50: 160nMpH: 7.4 T: 2°CAssay Description:The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Sapienza University of Rome

LigandPNGBDBM29144(substituted chalcone, 5k)
Affinity DataAssay Description:The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Sapienza University of Rome

LigandPNGBDBM29144(substituted chalcone, 5k)
Affinity DataIC50: 1.58E+5nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Sapienza University of Rome

LigandPNGBDBM29144(substituted chalcone, 5k)
Affinity DataIC50: 7.88E+4nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus-infected BTI cells using kynuramine as substrate incubated for 30 mins by fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Sapienza University of Rome

LigandPNGBDBM29144(substituted chalcone, 5k)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus-infected BTI cells using kynuramine as substrate incubated for 30 mins by fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed