BDBM29147 substituted chalcone, 5o

SMILES Fc1ccc(cc1)C(=O)\C=C\c1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=IWXGPHFRFJTQNH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 29147   

TargetAmine oxidase [flavin-containing] B(Human)
Sapienza University of Rome

LigandPNGBDBM29147(substituted chalcone, 5o)
Affinity DataIC50: 500nMpH: 7.4 T: 2°CAssay Description:The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Sapienza University of Rome

LigandPNGBDBM29147(substituted chalcone, 5o)
Affinity DataAssay Description:The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Sapienza University of Rome

LigandPNGBDBM29147(substituted chalcone, 5o)
Affinity DataIC50: 5.01E+5nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed