BDBM292009 US10100030, Example 4

SMILES CC1CN(CCC1CC(O)=O)c1cc(c(cn1)N(C)C(=O)C(C)(C)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)-c1ccc(F)cc1C

InChI Key InChIKey=AHUMDZDJKIBEFH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 292009   

TargetSubstance-P receptor(Human)
Kissei Pharmaceutical

US Patent
LigandPNGBDBM292009(US10100030, Example 4)
Affinity DataIC50: 3.54nMpH: 7.4 T: 2°CAssay Description:The buffer solution for the receptor binding test was dispensed to the wells of a 96-well assay plate (Greiner) at 22.5 uL/well. DMSO solutions of a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2019
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Kissei Pharmaceutical

US Patent
LigandPNGBDBM292009(US10100030, Example 4)
Affinity DataIC50: 4.80E+3nMpH: 7.4 T: 2°CAssay Description:A dimethyl sulfoxide (DMSO) solution of a test compound with a concentration 1000 times higher than the evaluation concentration was prepared, and a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2019
Entry Details
US Patent