BDBM292041 2-Cyclobutyl-3-(1H-indazol-5-yl)-5-(trifluoromethyl)-2H-pyrazolo[4,3-b]pyridine;::US10100045, Example 12

SMILES FC(F)(F)c1ccc2nn(C3CCC3)c(-c3ccc4[nH]ncc4c3)c2n1

InChI Key InChIKey=DKSHFNDBUUVGGO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 292041   

TargetVoltage-dependent calcium channel gamma-2 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM292041(US10100045, Example 12 | 2-Cyclobutyl-3-(1H-indazo...)
Affinity DataIC50: 0.631nMpH: 7.4Assay Description:Cell expressing the GRIA1o-CACNG8 fusion construct were grown in a monolayer in 96- or 384-well microtiter plates. They were washed with assay buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2019
Entry Details
US Patent