BDBM292090 4-[4-(1,2,3,3a,4,6,7,7a- octahydropyrrolo[3,4-c]pyridin-5-yl)-1-(4- cyclopropylphenyl)-6-oxopyrimidin-2-yl]- 2-fluorobenzonitrile::US10100046, Example 28::US9902719, Example 28

SMILES Fc1cc(ccc1C#N)-c1nc(cc(=O)n1-c1ccc(cc1)C1CC1)N1CCC2CNCC2C1

InChI Key InChIKey=VOLKYVYXKVIHMQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 292090   

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM292090(US10100046, Example 28 | 4-[4-(1,2,3,3a,4,6,7,7a- ...)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM292090(US10100046, Example 28 | 4-[4-(1,2,3,3a,4,6,7,7a- ...)
Affinity DataIC50: 100nMT: 2°CAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2019
Entry Details
US Patent