BDBM292383 N-(2-(dimethylamino)ethyl)-2-(5-phenylpyrazolo[1,5-a]pyrimidin-3-yl)isonicotinamide::US10100058, Example 39

SMILES CN(C)CCNC(=O)c1ccnc(c1)-c1cnn2ccc(nc12)-c1ccccc1

InChI Key InChIKey=YRSMLFJUIGFQTF-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 292383   

LigandPNGBDBM292383(US10100058, Example 39 | N-(2-(dimethylamino)ethyl...)
Affinity DataIC50: 137nMAssay Description:The biochemical activity of recombinant CaMKIIδ was measured by monitoring the phosphorylation of a target peptide using Homogenous Time Resolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2019
Entry Details
US Patent

LigandPNGBDBM292383(US10100058, Example 39 | N-(2-(dimethylamino)ethyl...)
Affinity DataEC50:  320nMAssay Description:CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2019
Entry Details
US Patent