BDBM293910 (S)-3-(5-Chloro-2- methylpyridin-3-yl)-1-(3- fluoro-2-methylphenyl)- N-hydroxycyclopent-2- enecarboxamide::US10106535, Example 36::US9617259, 36

SMILES Cc1ncc(Cl)cc1C1=C[C@](CC1)(C(=O)NO)c1cccc(F)c1C

InChI Key InChIKey=RKCKQADYDVNGMV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293910   

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293910(US10106535, Example 36 | (S)-3-(5-Chloro-2- methyl...)
Affinity DataIC50: 20nMAssay Description:5 μl of each solution of 1:20 diluted compound from above is transferred to a clear bottomed, black, 384-well assay plate using the Bravo or the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2019
Entry Details
Go to US Patent

TargetHistone deacetylase 4(Human)
Chdi Foundation

US Patent
LigandPNGBDBM293910(US10106535, Example 36 | (S)-3-(5-Chloro-2- methyl...)
Affinity DataIC50: 20nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
Go to US Patent