BDBM294414 US9586959, Compound 92

SMILES CN1CCN(CC1)C1=Nc2ncc(Cl)cc2C2OC(C)=NC12

InChI Key InChIKey=CTFQEBABEYTOLI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 294414   

TargetHistamine H4 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294414(US9586959, Compound 92)
Affinity DataIC50: 42nMpH: 7.5 T: 2°CAssay Description:In vitro profiling protein kinases was performed using the HotSpot assay platform. Briefly, specific kinase/substrate pairs along with required cofac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
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TargetHistamine H3 receptor(Human)
C&C Research Laboratories

US Patent
LigandPNGBDBM294414(US9586959, Compound 92)
Affinity DataIC50: 1.00E+8nMpH: 7.4 T: 2°CAssay Description:Each compound of the present invention prepared in the examples was prepared in DMSO into concentrations of 0.02, 0.06, 0.3 and 2 mM. 10 uL of the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
Go to US Patent