BDBM29618 3-(2-aminoethylamino)-7-(phenylmethyl)-1-[(phenylmethyl)amino]-6,8-dihydro-5H-2,7-naphthyridine-4-carbonitrile::3-(2-aminoethylamino)-7-benzyl-1-(benzylamino)-6,8-dihydro-5H-2,7-naphthyridine-4-carbonitrile::3-(2-azanylethylamino)-7-(phenylmethyl)-1-[(phenylmethyl)amino]-6,8-dihydro-5H-2,7-naphthyridine-4-carbonitrile::MLS000071217::SMR000038208::cid_657445

SMILES NCCNc1nc(NCc2ccccc2)c2CN(Cc3ccccc3)CCc2c1C#N

InChI Key InChIKey=PJYONHUMXQIGRJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 29618   

TargetEstrogen receptor(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM29618(MLS000071217 | SMR000038208 | 3-(2-aminoethylamino...)
Affinity DataIC50: 1.18E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: John A. Katzenellenbogen, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2011
Entry Details
PCBioAssay
TargetRunt-related transcription factor 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29618(MLS000071217 | SMR000038208 | 3-(2-aminoethylamino...)
Affinity DataIC50: 4.78E+4nMpH: 7.4 T: 2°CAssay Description:This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2009
Entry Details
PCBioAssay
TargetRunt-related transcription factor 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29618(MLS000071217 | SMR000038208 | 3-(2-aminoethylamino...)
Affinity DataIC50: 4.78E+4nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2009
Entry Details
PCBioAssay