BDBM29656 4-[(Pyridin-3-ylmethyl)-amino]-2,3-dihydro-1H-4a,9-diaza-cyclopenta[b]fluorene-10-carbonitrile::MLS000556361::SMR000147678::cid_702038

SMILES N#Cc1c2CCCc2c(NCc2cccnc2)n2c1nc1ccccc21

InChI Key InChIKey=GYVDMWVPDNIPMH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29656   

TargetRunt-related transcription factor 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29656(SMR000147678 | 4-[(Pyridin-3-ylmethyl)-amino]-2,3-...)
Affinity DataIC50: 5.35E+4nMpH: 7.4 T: 2°CAssay Description:This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2009
Entry Details
PCBioAssay
TargetRunt-related transcription factor 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29656(SMR000147678 | 4-[(Pyridin-3-ylmethyl)-amino]-2,3-...)
Affinity DataIC50: 5.35E+4nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2009
Entry Details
PCBioAssay