BDBM297367 5-(pyrimidin-4-ylamino)-3-(thiophen-3-yl)isoindolin-1-one (Cpd. No. 37)::US10112955, Example 37

SMILES O=C1NC(c2ccsc2)c2cc(Nc3ccncn3)ccc12

InChI Key InChIKey=KUHYGUXTOZBOFJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 297367   

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Effector Therapeutics

US Patent
LigandPNGBDBM297367(US10112955, Example 37 | 5-(pyrimidin-4-ylamino)-3...)
Affinity DataIC50: 10nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Effector Therapeutics

US Patent
LigandPNGBDBM297367(US10112955, Example 37 | 5-(pyrimidin-4-ylamino)-3...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
Go to US Patent