BDBM297373 5-((6-aminopyrimidin-4-yl)amino)-7-chloro-3,3-dimethylisoindolin-1-one (Cpd. No. 43)::US10112955, Example 43

SMILES CC1(C)NC(=O)c2c1cc(Nc1cc(N)ncn1)cc2Cl

InChI Key InChIKey=BMRWXFQLOMKCPL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 297373   

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Effector Therapeutics

US Patent
LigandPNGBDBM297373(US10112955, Example 43 | 5-((6-aminopyrimidin-4-yl...)
Affinity DataIC50: 10nMAssay Description:Compounds are screened for MNK inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Effector Therapeutics

US Patent
LigandPNGBDBM297373(US10112955, Example 43 | 5-((6-aminopyrimidin-4-yl...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
Go to US Patent