BDBM298317 N-((S)-3-cyclohexyl-1-(((S)-4-(cyclohexylamino)- 3,4-dione-1-((S)-2-oxopiperidin-3-yl)but- 2-yl)amino)-1-oxo-3-phenylpropan-2-yl)- benzofuran-2-carboxamide::US12636275, Compound A59

SMILES O=C(NC1CCCCC1)C(=O)[C@H](C[C@@H]1CCCNC1=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cc2ccccc2o1

InChI Key InChIKey=VJQHKUDRSJBZHM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 298317   

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 298317BDBM298317(N-((S)-3-cyclohexyl-1-(((S)-4-(cyclohexylamino)- 3...)
Affinity DataIC50: 2.35E+4nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent