BDBM298340 US10123995, Example 18

SMILES OC(=O)c1ccc(NC(=O)[C@@]2(F)C[C@H](F)c3cc(cnc23)-c2cc(Cl)ccc2-n2cnnn2)cc1

InChI Key InChIKey=JQFHMMXOQIRFDU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 298340   

TargetCoagulation factor XI(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM298340(US10123995, Example 18)
Affinity DataIC50: 9.45E+3nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent