BDBM29877 alkynyl ether, 19

SMILES OC(=O)COc1ccc(Sc2ccc(COc3ccc(cc3)C(F)(F)F)cc2OCC#C)c2CCCCc12

InChI Key InChIKey=ZCORSQTXEMWYOI-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 29877   

LigandPNGBDBM29877(alkynyl ether, 19)
Affinity DataKi:  7nM EC50:  52nMAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2009
Entry Details Article
PubMed
LigandPNGBDBM29877(alkynyl ether, 19)
Affinity DataKi:  960nM ΔG°:  -8.12kcal/mole EC50:  3.90E+3nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2009
Entry Details Article
PubMed
LigandPNGBDBM29877(alkynyl ether, 19)
Affinity DataKi:  1.20E+3nM EC50:  4.90E+3nMAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2009
Entry Details Article
PubMed