BDBM298815 US10125118, Example 221::US10947215, Example 221

SMILES Cn1cc(cn1)-c1cnc(N)c(c1)C(=O)N[C@H]1CCC[C@@H]1OCc1ccc(cc1)-c1ccc(cc1)C(C)(C)N1CCN(CCO)CC1

InChI Key InChIKey=BMHLOOSWUGXQCM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 298815   

TargetTyrosine-protein kinase Mer(Human)
Abbvie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 298815BDBM298815(US10125118, Example 221 | US10947215, Example 221 ...)
Affinity DataIC50: 0.290nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein kinase Mer(Human)
Abbvie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 298815BDBM298815(US10125118, Example 221 | US10947215, Example 221 ...)
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Abbvie, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 298815BDBM298815(US10125118, Example 221 | US10947215, Example 221 ...)
Affinity DataIC50: 0.800nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Abbvie, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 298815BDBM298815(US10125118, Example 221 | US10947215, Example 221 ...)
Affinity DataIC50: 0.900nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein kinase Mer/receptor UFO(Human)
Dong-A Socio Holdings

US Patent
LigandChemical structure of BindingDB Monomer ID 298815BDBM298815(US10125118, Example 221 | US10947215, Example 221 ...)
Affinity DataIC50: 10nMAssay Description:For the SAR (structure-activity relationship) and compound screening, LanthaScreen TR-FRET (Time-Resolved fluorescence energy transfer) assay was emp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Abbvie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 298815BDBM298815(US10125118, Example 221 | US10947215, Example 221 ...)
Affinity DataIC50: 10nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Abbvie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 298815BDBM298815(US10125118, Example 221 | US10947215, Example 221 ...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Abbvie, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 298815BDBM298815(US10125118, Example 221 | US10947215, Example 221 ...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details US Patent

TargetTyrosine-protein kinase Mer(Human)
Abbvie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 298815BDBM298815(US10125118, Example 221 | US10947215, Example 221 ...)
Affinity DataEC50:  19nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein kinase Mer(Human)
Abbvie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 298815BDBM298815(US10125118, Example 221 | US10947215, Example 221 ...)
Affinity DataEC50:  19nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
Abbvie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 298815BDBM298815(US10125118, Example 221 | US10947215, Example 221 ...)
Affinity DataIC50: 167nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetActivated CDC42 kinase 1(Human)
Abbvie, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 298815BDBM298815(US10125118, Example 221 | US10947215, Example 221 ...)
Affinity DataIC50: 188nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 298815BDBM298815(US10125118, Example 221 | US10947215, Example 221 ...)
Affinity DataIC50: 435nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 5(Homo sapiens)
Abbvie, Inc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 298815BDBM298815(US10125118, Example 221 | US10947215, Example 221 ...)
Affinity DataIC50: 530nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosinase(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 298815BDBM298815(US10125118, Example 221 | US10947215, Example 221 ...)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details US Patent