BDBM29973 arylpyrazole, 18

SMILES Cc1c(CNC2CCCC2)nn(c1-c1ccc(Cl)nc1)-c1ncccc1Cl

InChI Key InChIKey=DLZARUDZVNDGHQ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29973   

TargetNociceptin receptor(Human)
Banyu Pharmaceutical

LigandPNGBDBM29973(arylpyrazole, 18)
Affinity DataIC50: 11nM EC50:  12nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2009
Entry Details Article
PubMed
LigandPNGBDBM29973(arylpyrazole, 18)
Affinity DataIC50: 2.70E+3nMpH: 7.4 T: 2°CAssay Description:Binding affinity to the hERG K+ channel was measured by displacement of [35S]-radiolabeled MK499 in membranes derived from HEK 293 cells stably trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2009
Entry Details Article
PubMed