BDBM29993 2-Cyclohexylcarbonylbenzimidazole, 7d

SMILES CCN1CCN(CC1)c1cc2[nH]c(nc2cc1Cl)C(=O)[C@@]1(C)CC[C@@](C)(O)CC1

InChI Key InChIKey=NXSFKUCSWRJBEE-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29993   

TargetNociceptin receptor(Human)
Banyu Pharmaceutical

LigandBDBM29993(2-Cyclohexylcarbonylbenzimidazole, 7d)Copy SMILESCopy InChI

Affinity DataIC50: 27nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
7/4/2009
Entry Details Article
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Banyu Pharmaceutical

LigandBDBM29993(2-Cyclohexylcarbonylbenzimidazole, 7d)Copy SMILESCopy InChI

Affinity DataIC50: 3.10E+3nMpH: 7.4 T: 2°CAssay Description:Binding affinity to the hERG K+ channel was measured by displacement of [35S]-radiolabeled MK499 in membranes derived from HEK 293 cells stably trans...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
7/4/2009
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL