BDBM301823 N-cyclohexyl-3-((2,3-dichlorophenethyl)amino)-N-(2-((2-(2-methylindolizin-1-yl)ethyl)amino)ethyl)propanamide::US9598381, 16

SMILES Cc1cn2ccccc2c1CCNCCN(C1CCCCC1)C(=O)CCNCCc1cccc(Cl)c1Cl

InChI Key InChIKey=OHMKSYWEJXELNI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 301823   

TargetN-lysine methyltransferase SMYD2(Human)
Abbvie

US Patent
LigandPNGBDBM301823( N-cyclohexyl-3-((2,3-dichlorophenethyl)amino)-N-(...)
Affinity DataIC50: 3.44E+3nMAssay Description:Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
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