BDBM301933 US9598396, Compound 8

SMILES CC(Cc1cccc(Cl)c1)(C#N)c1ccc2c3CCCCc3c(=O)[nH]c2c1

InChI Key InChIKey=RMPXVEDDRZOQIA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 301933   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM301933(US9598396, Compound 8)
Affinity DataIC50: 52.5nMAssay Description:In principle, the assay relies upon the well established SPA technology for the detection of poly(ADP-ribosyl)ation of biotinylated target proteins, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM301933(US9598396, Compound 8)
Affinity DataIC50: 83.2nMAssay Description:Compounds of the present invention were tested in an in vitro assay based on SPA technology with Ni Flash plates (96 or 384 well).In principle, the a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent