BDBM302008 US9598405, 2.7

SMILES Cc1cc(Nc2cc(CC(O)=O)ccn2)nc(c1)-c1cnc(s1)C1(O)CCC(CC1)C(O)=O

InChI Key InChIKey=QMQZNFNZVYFTTI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 302008   

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM302008(US9598405, 2.7)
Affinity DataIC50: 1.01nMAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent