BDBM303229 US10137122, Compound 108::US11203601, Compound Table 1.17

SMILES CC1(C)CC(=O)C2=C(C1)Nc1n[nH]cc1[C@]2(C)c1ccccc1

InChI Key InChIKey=IMKJGRXMBFNOGA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 303229   

TargetGlycogen synthase kinase-3 alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM303229(US10137122, Compound 108 | US11203601, Compound Ta...)
Affinity DataIC50: 42nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
The Broad Institute

US Patent
LigandPNGBDBM303229(US10137122, Compound 108 | US11203601, Compound Ta...)
Affinity DataIC50: 225nMAssay Description:A selection of compounds was screened against a selected panel of kinases based on single point inhibitory ability to determine absolute inhibitory a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2022
Entry Details
US Patent

TargetGlycogen synthase kinase-3 alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM303229(US10137122, Compound 108 | US11203601, Compound Ta...)
Affinity DataIC50: 550nMAssay Description:A solution of 4× inhibitor (5 μL), 4× substrate/ATP-Metal solution (5 μL), and 2× Kinase solution (10 μL) was prepared with assay buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent