BDBM3037 23-[3-(dimethylamino)propyl]-7,19-dimethoxy-3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tricosa-1(16),2(10),4,6,8,11(15),17(22),18,20-nonaen-12-one::Indolocarbazole deriv. 3e

SMILES COc1ccc2[nH]c3c(c4C(=O)NCc4c4c5cc(OC)ccc5n(CCCN(C)C)c34)c2c1

InChI Key InChIKey=TZAHMEHTLQVSPK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 3037   

TargetMyosin light chain kinase, smooth muscle(Chicken)
Tumor Biology Center

LigandPNGBDBM3037(23-[3-(dimethylamino)propyl]-7,19-dimethoxy-3,13,2...)
Affinity DataIC50: 220nMpH: 7.2 T: 2°CAssay Description:The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2005
Entry Details Article

TargetProtein kinase C beta type(Rat)
Tumor Biology Center

LigandPNGBDBM3037(23-[3-(dimethylamino)propyl]-7,19-dimethoxy-3,13,2...)
Affinity DataIC50: 550nMAssay Description:The activity of MLCK is measured by its ability to transfer 32P from [gamma-32P]ATP to myosin light-chain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2005
Entry Details Article

TargetMyosin light chain kinase, smooth muscle(Human)
Tumor Biology Center

LigandPNGBDBM3037(23-[3-(dimethylamino)propyl]-7,19-dimethoxy-3,13,2...)
Affinity DataIC50: 220nMAssay Description:The activity of cGPK, activated by cGMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2005
Entry Details Article