BDBM30497 1,1-dioxoisothiazole analog., 41

SMILES CS(=O)(=O)NCc1cccc2C(NS(=O)(=O)c12)=C1C(=O)N(Cc2ccc(F)c(Cl)c2)C2(CC2)C1=O

InChI Key InChIKey=QIGSAQAAMDQGNW-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 30497   

TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandPNGBDBM30497(1,1-dioxoisothiazole analog., 41)
Affinity DataIC50: 130nM EC50: >3.30E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2009
Entry Details Article
PubMed