BDBM30510 5,6-Dihydro-1H-pyridin-2-one, 4j

SMILES CC(C)(C)CCN1C2CCCCCC2C(=O)C(C1=O)C1=Nc2ccc(NS(C)(=O)=O)cc2S(=O)(=O)N1

InChI Key InChIKey=LTNWUJNWPUDEDK-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 30510   

TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandPNGBDBM30510(5,6-Dihydro-1H-pyridin-2-one, 4j)
Affinity DataIC50: 39nM EC50:  22nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandPNGBDBM30510(5,6-Dihydro-1H-pyridin-2-one, 4j)
Affinity DataIC50: 73nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed