BDBM30516 5,6-Dihydro-1H-pyridin-2-one, 4p

SMILES CC(C)CCN1C2CCCC2C(=O)C(C2=Nc3ccc(NS(C)(=O)=O)cc3S(=O)(=O)N2)C1=O

InChI Key InChIKey=CUYSZQLWQBMVFV-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 30516   

TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandPNGBDBM30516(5,6-Dihydro-1H-pyridin-2-one, 4p)
Affinity DataIC50: 10nM EC50:  60nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandPNGBDBM30516(5,6-Dihydro-1H-pyridin-2-one, 4p)
Affinity DataIC50: 25nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed