BDBM30525 5,6-Dihydro-1H-pyridin-2-one, 4y

SMILES CS(=O)(=O)Nc1ccc2N=C(NS(=O)(=O)c2c1)C1C(=O)C2CCCC2N(Cc2ccc(F)cn2)C1=O

InChI Key InChIKey=ADTUHMOANHJXBG-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 30525   

TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandPNGBDBM30525(5,6-Dihydro-1H-pyridin-2-one, 4y)
Affinity DataIC50: 120nM EC50:  3.10E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
Anadys Pharmaceuticals

LigandPNGBDBM30525(5,6-Dihydro-1H-pyridin-2-one, 4y)
Affinity DataIC50: 190nMAssay Description:Assays were performed in a 96-well streptavidin-coated Flash-Plate using enzyme, RNA substrate, and [alpha-33P]GTP/GTP with inhibitor concentration v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2009
Entry Details Article
PubMed