BDBM306711 US10149835, Example 2

SMILES Clc1cccc(Cl)c1-c1noc(C2CC2)c1COC1CC2CC[C@@H](C1)N2c1nc2ccc(cc2s1)C(=O)NS(=O)(=O)C1CC1

InChI Key InChIKey=UCNYNWDGBJXVKD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 306711   

TargetBile acid receptor(Human)
Elmore Patent Law Group

US Patent
LigandPNGBDBM306711(US10149835, Example 2)
Affinity DataEC50: <100nMAssay Description:Determination of a ligand mediated Gal4 promoter driven transactivation to quantify ligand binding mediated activation of FXR. FXR Reporter Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2019
Entry Details
US Patent