BDBM309354 (S)-tert-butyl (1-amino-4-((6-(4-(4-fluorophenoxy)phenyl)pyridin-2-yl)amino)-1,4-dioxobutan-2-yl)carbamate::US9656959, Example 40

SMILES CC(C)(C)OC(=O)N[C@@H](CC(=O)Nc1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1)C(N)=O

InChI Key InChIKey=TZYGZFPLGMUHNM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 309354   

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM309354(US9656959, Example 40 | (S)-tert-butyl (1-amino-4-...)
Affinity DataIC50: 130nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2019
Entry Details
US Patent