BDBM309362 N-((S)-1-{6-[4-(4-Fluoro-phenoxy)-phenyl]-pyridin-2-ylcarbamoyl}-2-hydroxy-ethyl)-nicotinamide::US9656959, Example 56

SMILES OC[C@H](NC(=O)c1cccnc1)C(=O)Nc1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1

InChI Key InChIKey=YQPBPOXSYOPRAF-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 309362   

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM309362(US9656959, Example 56 | N-((S)-1-{6-[4-(4-Fluoro-p...)
Affinity DataIC50: 140nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2019
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM309362(US9656959, Example 56 | N-((S)-1-{6-[4-(4-Fluoro-p...)
Affinity DataKi:  195nMAssay Description:In the alternative, the voltage clamp protocol to examine hNav1.7 currents was as follows. First, the standard current-voltage relationship was teste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2019
Entry Details
US Patent